IVUS VS CAG Guided PCI for Patients With LMB Lesion (NCT04072003) | Clinical Trial Compass
UnknownNot Applicable
IVUS VS CAG Guided PCI for Patients With LMB Lesion
616 participantsStarted 2019-09
Plain-language summary
To compare the 3 - year clinical follow - up results of patients with left main bifurcation lesions treated by intravascular ultrasound(IVUS) - guided and coronary angiography(CAG) - guided percutaneous coronary intervention(PCI), and to confirm the clinical benefits of optimizing interventional therapy of left main bifurcation lesions by intravascular ultrasound(IVUS).
Who can participate
Age range18 Years – 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patients with stable or unstable angina pectoris, asymptomatic myocardial ischemia or attack of myocardial infarction \>24 h;
✓. True bifurcation lesion of left main coronary artery (Medina 1,1,1 or 0,1,1);
✓. According to coronary angiography, the opening stenosis of the left anterior descending (LAD) and left circumflex (LCX) is more than 50% visually;
✓. The operator judges that the lesion is suitable for drug eluting stent(DES) implantation;
✓. Branch vessel diameter ≥2.5 mm by visual inspection;
Exclusion criteria
✕. Pregnant or lactating women;
✕. Combined with other diseases, life expectancy \<1 year;
✕. A surgery is scheduled within 6 months after the operation, and this surgery affects continuous administration of antiplatelet drugs;
✕. The dual antiplatelet therapy cannot be tolerated;
✕. Follow - up visits required by the protocol cannot be followed, or the investigators believe that the participation of subjects in the trial will increase the risk;
✕. Unable to provide written informed consent form, or unable to follow the trial protocol;
✕. Participate in another clinical trial of coronary interventional device;
What they're measuring
1
Target vessel failure rate(the rate of outcomes including cardiac death, target vessel myocardial infarction(MI), and clinically driven main branch or side branch target vessel revascularization(TVR) in each group)