SuspendedPhase 2/3

Does DHEA IVF Outcomes in Poor Responders?

Stopped: Sponsor

United Kingdom400 participantsStarted 2017-10-08

Plain-language summary

This study is a RCT to examine whether DHEA is capable of improving results for poor responders to ovarian stimulation during IVF treatment

Who can participate

Age range40 Years – 42 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 40 years * Markers for poor ovarian reserve (AMH \<7 pmol/L(\<1.1 ng/ml) and/or AFC\< 7) * Previous poor response to ovarian stimulation ( ≤3 oocytes with a conventional stimulation protocol) Exclusion Criteria: * Women \> 42 years * Women with premature ovarian failure / premature menopause (FSH\>40 U/L). Women already taking DHEA. * Patients with a known allergy to the trial drug or any of the active ingredients in the placebo.

What they're measuring

Clinical pregnancy rates

Timeframe: at 6-8 weeks gestation

Trial details

NCT IDNCT04066478

SponsorHomerton University Hospital NHS Foundation Trust

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-31

View on ClinicalTrials.gov More Infertility, Female trials