The goal of this observational study is to compare clinical outcomes of two techniques for sperm cell sorting, microfluidic sorting and magnetic activated cell sorting (MACS) technique, in males with high DNA fragmentation within an assisted reproductive treatment. The main questions it aims to answer are: * Does microfluidic sorting improve pregnancy rate compared to MACS? * Does microfluidic sorting improve fertilization rate compared to MACS? * Does microfluidic sorting improve implantation rate compared to MACS? * Does microfluidic sorting improve blastocyst development rate compared to MACS? Participants will deposit an eyaculate sample that will be analyzed for DNA fragmentation using a aliquot, then split in two to perform MACS and the microfluidic sorting. Both will be tested for DNA fragmentation (aliquotes) and used for the ICSI treatment with donor oocytes. Researchers will compare both techniques to see if the selection of the best functional spermatozoa with less DNA fragmentation and clinical outcomes improve.
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Pregnancy rate
Timeframe: Mar 2019 - Oct 2021