Active — Not RecruitingNot Applicable

Exercise, Arterial Modulation and Nutrition in Youth South Africa Study

South Africa1,065 participantsStarted 2017-09-12

Plain-language summary

The ExAMIN Youth SA study aims to generate new knowledge on the pathophysiology involved in early vascular aging among South African children and to identify early novel biological markers for predicting the subclinical development of hypertension and target organ damage related to cardiovascular disease. This study further implements state-of-the-art biochemical technology to measure a variety of biological markers including multiplex analyses and metabolomics. With the increasing prevalence of childhood hypertension and obesity, this study will be able to address especially behavioural contributors to hypertension development and to subsequently provide a backdrop for school-based primary prevention interventions.

Who can participate

Age range

62 Months – 129 Months

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children between ages 5 and 9 years (both sexes and all ethnicities). Exclusion Criteria: * Children who do not wish to participate or where the parents or caregivers did not provide permission.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

To determine blood pressure classification among primary school children in South Africa

Timeframe: Through study completion, an average of 1 year

To determine overweight and obesity prevalence among primary school children in South Africa

Timeframe: Through study completion, an average of 1 year

To identify novel biomarkers in predicting elevated blood pressure in primary school children from South Africa

Timeframe: Through study completion, an average of 1 year

Trial details

NCT IDNCT04056377

SponsorNorth-West University, South Africa

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-04-30

View on ClinicalTrials.gov More Hypertension trials

Plain-language summary

Who can participate

Age range

62 Months – 129 Months

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

To determine blood pressure classification among primary school children in South Africa

Timeframe: Through study completion, an average of 1 year

To determine overweight and obesity prevalence among primary school children in South Africa

Timeframe: Through study completion, an average of 1 year

To identify novel biomarkers in predicting elevated blood pressure in primary school children from South Africa

Timeframe: Through study completion, an average of 1 year