'CHIP' stands for Clonal Hematopoiesis of Indeterminate Significance, which are mutations in bone marrow stem cells that give that population of cells a survival or 'clonal' advantage for growth. This study investigates whether CHIP in lymphoma patients aged 60 years and older is a risk factor for chemotherapy-related complications like low blood counts, infections, cardiac events, hospitalizations, dose delays and dose reductions, and failure to recover normal blood counts after chemotherapy finishes.
Age range
60 Years
Sex
ALL
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Determine if CHIP is an independent risk factor for chemotherapy-induced complications.
Timeframe: Up to 24 weeks
Emerging dysmyelopoiesis after chemotherapy
Timeframe: Up to 12 months after completion of chemotherapy
Prasha Sasitharakumar, MHSc