'CHIP' stands for Clonal Hematopoiesis of Indeterminate Significance, which are mutations in bone marrow stem cells that give that population of cells a survival or 'clonal' advantage for growth. This study investigates whether CHIP in lymphoma patients aged 60 years and older is a risk factor for chemotherapy-related complications like low blood counts, infections, cardiac events, hospitalizations, dose delays and dose reductions, and failure to recover normal blood counts after chemotherapy finishes.
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Determine if CHIP is an independent risk factor for chemotherapy-induced complications.
Timeframe: Up to 24 weeks
Emerging dysmyelopoiesis after chemotherapy
Timeframe: Up to 12 months after completion of chemotherapy
Prasha Sasitharakumar, MHSc