Progestin Priming Ovarian Stimulation (PPOS) Compared With Antagonist Protocol for Freeze-all Cycles (NCT04052607) | Clinical Trial Compass
TerminatedNot Applicable
Progestin Priming Ovarian Stimulation (PPOS) Compared With Antagonist Protocol for Freeze-all Cycles
Stopped: Due to COVID19 Pandemic effect on 2020.
Egypt56 participantsStarted 2019-09-10
Plain-language summary
Stimulation protocols for IVF underwent several cycles of upgrading aiming to achieve reasonable outcomes with low-cost cycles. Antagonist protocols have been introduced as effective and comparable to long agonist regarding the outcomes. However, these protocols are still costly. Alternative protocols using progestin suppressions appear options for consideration.
Who can participate
Age range18 Years – 40 Years
SexFEMALE
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Inclusion criteria
✓. Women age of ≥ 18 to ≤ 40;
✓. BMI of ≤ 31;
✓. All indication for freeze-all
✓. PCOS;
✓. Women who have ≥ 1 year of primary or secondary infertility;
✓. Tubal factor (unilateral, bilateral obstruction or salpingectomy);
✓. Fresh ejaculate sperm of any count provided they have ≥ 1% normal forms and a motile fraction;
✓. Women undergoing their first ICSI cycle or following a previous successful attempt;
Exclusion criteria
✕. Unilateral oophorectomy;
✕. Uterine pathology or abnormality;
✕. Abnormal karyotyping for them or their male partners;