Active — Not RecruitingNot Applicable

Reversal of Neuromuscular Blockade During the General Anaesthesia

Finland120 participantsStarted 2020-04-08

Plain-language summary

There are individual reports indicating that after the reversal of nondepolarizing neuromuscular blockade with neostigmine, some patients starts to relax spontaneously again after the tof ratio has already recovered to the safe level (\>90%). The mechanism behind this in not well understood, and the incidence of the phenomenon is unclear. In this study the investigators try to determine the incidence of the aforementioned postrecovery relaxation.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion Criteria: * Elective surgery requiring general anaesthesia * Surgery is assumed to last more than 45 minutes * Body mass index less than 35kg/ m² Exclusion Criteria: * Disease of central nervous system * Trauma of central nervous system * Disease affecting peripheral nervous system * Medication affecting peripheral nervous system

What they're measuring

Incidence of postrecovery relaxation

Timeframe: 30 minutes

Trial details

NCT IDNCT04048655

SponsorTampere University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09-01

View on ClinicalTrials.gov More Neuromuscular Blockade trials