The overall purpose of the proposed pilot study is to establish the feasibility of conducting a clinical trial by evaluating the preliminary effects of 8 weeks of knee bracing on physiological measures of self-reported pain and disability, physical performance, physical activity, as well as femoral cartilage deformation in individuals with medial compartment knee osteoarthritis (OA). The investigators will recruit 36 symptomatic knee OA patients for the pilot study. The investigators will evaluate a class of braces (two different models will be used) designed to correct genu varum. The purpose of the study is to evaluate changes in these novel outcomes following the use of a class of braces used to reduce medial tibiofemoral compartment compression used for 8 weeks. This pilot study will inform a larger future trial to determine the efficacy of bracing on decreasing disability and disease progression in patients with knee osteoarthritis.
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Percentage Change in WOMAC Function score from Baseline to 8 weeks
Timeframe: Baseline, Week 8 (Followup)
Percentage Change in Physical Activity Scale for the Elderly from Baseline to 8 weeks
Timeframe: Baseline, Week 8 (Followup)
Percentage Change in 30-s chair-stand test from Baseline to 8 weeks
Timeframe: Baseline, Week 8 (Followup)
Percentage Change in 20 meter fast-paced walk test from Baseline to 8 weeks
Timeframe: Baseline, Week 8 (Followup)
Percentage Change in Stair-climb test from Baseline to 8 weeks
Timeframe: Baseline, Week 8 (Followup)
Percentage Change in Femoral Cartilage Cross-sectional area from Baseline to 8 weeks
Timeframe: Baseline, Week 8 (Followup)