UnknownPhase 4

Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

South Korea47 participantsStarted 2017-07-01

Plain-language summary

The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction. The hypothesis of the study was that patients treated with intraarticular tranexamic acid would have significantly less postoperative hemarthrosis and less pain in the early phase of the rehabilitation process compared with those without intraarticular tranexamic acid .

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * primary single bundle anterior cruciate ligament reconstruction using a hamstring autograft with or without meniscus surgeries Exclusion Criteria: * use of other grafts (allograft, bone patellar tendon bone autograft) * revision anterior cruciate ligament reconstruction, * concomitant knee cartilage or collateral ligament surgeries * history of knee surgery on affected knee * concomitant fracture * significnat preoperative pain (Visual analoge score \>5) * coagulation or bleeding disorders * preoperative anticoagulation treatment

What they're measuring

blood loss

Timeframe: 2 days

Trial details

NCT IDNCT04042688

SponsorKorea University Guro Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-06-20

View on ClinicalTrials.gov More Anterior Cruciate Ligament Rupture trials