UnknownNot Applicable

CPET in Evaluation of PH in COPD Patients

50 participantsStarted 2019-10-01

Plain-language summary

* To evaluate the entire course of exercise during CPET in COPD patients. * To study whether CPET, PFTs and arterial blood gases could discriminate between COPD patients with and without PH. * To study whether the existence of pulmonary hypertension in COPD is related to characteristic findings in gas exchange and circulatory parameters during cardiopulmonary exercise testing (CPET).

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Stable COPD patients * with age ≥ 40 years. * Prior to inclusion, the COPD diagnosis was verified by spirometry before and after bronchodilation. * treatment was optimized and Patients on regular medication. Exclusion Criteria: * Patients who refuse to participate in the study. * Patients underwent thorough pulmonary and cardiologic preinclusion screening, and those with pulmonary disease other than COPD and emphysema. * arrhythmia * valvular or coronary heart disease * left ventricle dysfunction * obstructive sleep apnea syndrome * pulmonary embolism * systemic hypertension ≥160/90 mmHg * inflammatory disease * hyperthyroidism * renal failure * inability to exercise (due to orthopedic, neurologic or musculoskeletal problem).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Measurement of oxygen uptake during cardiopulmonary exercise testing (% predicted)

Timeframe: Baseline

Measurement the arterial pO2 in mmHg and arterial pCO2 at baseline

Timeframe: Baseline

Trial details

NCT IDNCT04035148

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-10

Contact for this trial

Amira Emad El-din

+201019937498 tota_eg1993@yahoo.com

View on ClinicalTrials.gov More COPD trials