UnknownNot Applicable

CPET in Evaluation of PH in COPD Patients

50 participantsStarted 2019-10-01

Plain-language summary

* To evaluate the entire course of exercise during CPET in COPD patients. * To study whether CPET, PFTs and arterial blood gases could discriminate between COPD patients with and without PH. * To study whether the existence of pulmonary hypertension in COPD is related to characteristic findings in gas exchange and circulatory parameters during cardiopulmonary exercise testing (CPET).

Who can participate

Age range40 Years – 80 Years

SexALL

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Inclusion Criteria: * Stable COPD patients * with age ≥ 40 years. * Prior to inclusion, the COPD diagnosis was verified by spirometry before and after bronchodilation. * treatment was optimized and Patients on regular medication. Exclusion Criteria: * Patients who refuse to participate in the study. * Patients underwent thorough pulmonary and cardiologic preinclusion screening, and those with pulmonary disease other than COPD and emphysema. * arrhythmia * valvular or coronary heart disease * left ventricle dysfunction * obstructive sleep apnea syndrome * pulmonary embolism * systemic hypertension ≥160/90 mmHg * inflammatory disease * hyperthyroidism * renal failure * inability to exercise (due to orthopedic, neurologic or musculoskeletal problem).

What they're measuring

Measurement of oxygen uptake during cardiopulmonary exercise testing (% predicted)

Timeframe: Baseline

Measurement the arterial pO2 in mmHg and arterial pCO2 at baseline

Timeframe: Baseline

Trial details

NCT IDNCT04035148

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-10

Contact for this trial

Amira Emad El-din

+201019937498 tota_eg1993@yahoo.com

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