This will be a prospective study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic effects, side effects to perioperative analgesics, chronic postoperative pain, and gene expression in patients following pectus excavatum repair.
Age range
8 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Pain score trajectory
Timeframe: 1 year
Changes in self-reported psychosocial scores (including anxiety, pain, coping, physical limitation, etc.)
Timeframe: 1 year
Changes in heart rate variability
Timeframe: 8 weeks
Changes in mean amplitude values for lower, upper, and entire alpha frequency bands by group (intervention/no intervention) and time (pre-surgery/post-surgery)
Timeframe: 8 weeks
Changes in evoked response potentials (ERPs) during meditation and experimental pain tasks
Timeframe: 8 weeks
Changes in sleep efficiency/duration (actigraphy) and self-reported sleep quality
Timeframe: 8 weeks
Incidence of side-effect measures
Timeframe: 72 hours postoperatively