Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods

Inclusion criteria for aggressive periodontitis patients; * The periodontal diagnosis of subjects with GAgP was established on the basis of clinical and radiographic criteria and was defined by the 1999 International World Workshop for a Classification of Periodontal Diseases and Conditions (Lang et al., 1999), * Between 18 and 35 years of age, * Otherwise healthy, * The bone loss estimation was radiographically performed in each patient for the assessment of the extent and severity of alveolar bone loss. Inclusion criteri for chronic periodontitis patients; * Had at least 20 teeth, * Exhibiting \>30% of measured sites with 5mm clinical attachment loss,, * Had bleeding on probing (BOP) at \>50% of the proximal sites. Inclusion criteri for control individuals; \- Overall healthy individuals (dental, periodontal and systemically) Exclusion Criteria for all individuals; * Had any known systemic diseases or conditions that can/could influence the periodontal status (cancer, cardiovascular and respiratory diseases), * Any history of hepatitis and/or HIV infection, * Immunosuppressive chemotherapy, * Current pregnancy, planning a pregnancy or lactation, * Requirement for antibiotic prophylaxis, * Had oral diseases other than GAgP, * Oongoing orthodontic therapy, * A history of antibiotic therapy, or periodontal treatment within the preceding six months