This is an observational, non-interventional study that will recruit Healthy Volunteers (HV) and subjects with clinically confirmed Schizophrenia (SZ). The purpose of this study is to establish the mean and variance across the HV and SZ cohorts, sites, and repeated tests of the electroencephalogram(EEG)/Event-related potentials (ERP) measures.
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Amplitude (in microvolts) for parameters from the ERP tests.
Timeframe: 12-18 months
Latency (in milliseconds) for parameters from the ERP tests.
Timeframe: 12-18 months
Task accuracy from the behavioral response during the active, auditory oddball ERP test.
Timeframe: 12-18 months
Reaction time from the behavioral response during the active, auditory oddball ERP test.
Timeframe: 12-18 months
Total Power from the auditory steady-state response (ASSR) paradigm.
Timeframe: 12-18 months
Inter-trial coherence (ITC) from the auditory steady-state response (ASSR) paradigm.
Timeframe: 12-18 months
Absolute Power for Pharmaco-EEG parameters per IPEG guidelines.
Timeframe: 12-18 months
Relative Power for Pharmaco-EEG parameters per IPEG guidelines.
Timeframe: 12-18 months
Dominant frequency in the Alpha frequency band per IPEG guidelines
Timeframe: 12-18 months
Theta/Beta ratio and Slow Wave index per IPEG guidelines.
Timeframe: 12-18 months
Functional assessments as derived from the Brief Assessment of Cognition in Schizophrenia (BACS).
Timeframe: 12-18 months
Functional assessments as derived from the Positive and Negative Symptom Scale for Schizophrenia (PANSS).
Timeframe: 12-18 months
Functional assessments as derived from the Virtual Reality Functional Capacity Assessment Tool (VRFCAT).
Timeframe: 12-18 months