High Intensity Interval Training in Endometrial Cancer (NCT04025229) | Clinical Trial Compass
CompletedNot Applicable
High Intensity Interval Training in Endometrial Cancer
United States30 participantsStarted 2019-09-23
Plain-language summary
This interventional trial recruits women with endometrial cancer to participate in high intensity interval training (HIIT) prior to their standard of care surgery. The study will evaluate tissue and blood to determine if HIIT training has anti-cancer effects. P
Who can participate
Age range
18 Years – 75 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with a diagnosis of endometrial cancer who are to undergo hysterectomy and staging
* Between 40-75 years old
* Body mass index of 30-50 kg/m2
* Endometrioid histology endometrial cancer
* Presumed clinically early stage disease (disease confined to uterus only)
* Have access to a Smart Phone
* Have access to email
* Agree to visit the exercise and sport science laboratory within 2 days of SOC visit for baseline testing if enrollment procedures cannot be done on the same day.
Agree to visit clinic 2 (+/-2wks) weeks after surgery for SOC follow-up and post surgery visit, or willing to return to exercise and sport science laboratory 2 (+/-2wks) weeks post-surgery
Exclusion Criteria:
* Meets American College of Sports Medicine Guidelines for physical activity (150 minutes / week)
* Currently doing HIIT
* Hospitalization for a stroke, heart attack, or heart failure, or had surgery for blocked arteries in the past 3 months
* Active diagnosis of psychosis or current uncontrolled substance abuse disorder
* Insulin-dependent diabetes
* Currently in another EC intervention
* Severe dementia or other memory loss condition
* Severe mental health disorder
* Severely impaired hearing or speech
* Inability to speak English
* Musculoskeletal or neuromuscular condition that limits physical activity Any condition, in the opinion of the investigators, which would prohibit safe participation.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Proliferative Markers in Endometrium Before and After HIIT Exercises