CompletedNot Applicable

An Investigational Scan (Magnetic Resonance Elastography) in Detecting Treatment Response in Patients With Advanced Liver Cancer

United States6 participantsStarted 2019-06-11

Plain-language summary

This trial studies how well an investigational scan (magnetic resonance elastography \[MRE\]) works with standard imaging (magnetic resonance imaging \[MRI\]) in detecting response to treatment in patients with liver cancer that has spread to other places in the body. Diagnostic procedures, such as MRE with MRI, may make it easier for researchers to see if the treatment for liver cancer is working.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Liver cancer. * Available tumor and liver parenchyma tissue (biopsy-proven HCC). * No contraindications to MRI (such implanted ferromagnetic or pump devices, metallic fragments in eye), as indicated on our departmental MRI screening form. * Able to undergo informed consent. * Not pregnant. Exclusion Criteria: * Contraindication to MRI (including cardiac pacemaker; ferromagnetic foreign objects in the patient; metallic eye fragments; claustrophobia). * Inability to comply with study and/or follow-up procedures.

What they're measuring

Change in magnetic resonance elastography (MRE) liver tumor stiffness

Timeframe: Baseline to 6 weeks

Change in percent non-viable/necrotic tumor

Timeframe: Baseline to 6 weeks

Trial details

NCT IDNCT04022746

SponsorM.D. Anderson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-13

View on ClinicalTrials.gov More Advanced Adult Hepatocellular Carcinoma trials