CompletedNot Applicable

Acute Effects of Alcohol Use on Chronic Orofacial Pain

United States48 participantsStarted 2019-11-05

Plain-language summary

Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions of pain chronification and alcohol-related expectations and conditioning have not been previously studied. This project addresses this gap in knowledge and will inform further research and clinical/translational efforts for reducing risk associated with these behaviors.

Who can participate

Age range21 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Positive diagnosis of jaw pain, including temporomandibular joint and muscle disorder (TMD) (jaw pain group only) * Consume at least 1 drink/month over the past 6 months Exclusion Criteria: * History of chronic pain other than jaw pain or TMD * Current use of opioids * Current major depression * History of any psychotic disorder * Undercontrolled hypertension or diabetes * History of neurologic disease * History of serious medical illness * History of drug or alcohol dependence, including nicotine, or a pattern of hazardous alcohol use

What they're measuring

Pressure Pain Threshold

Timeframe: Day 1; Day 2 (Laboratory sessions will be separated by at least 48 hours.)

Pressure Pain Intensity

Timeframe: Day 1; Day 2 (Laboratory sessions will be separated by at least 48 hours.)

Perceived Relief

Timeframe: Day 1; Day 2 (Laboratory sessions will be separated by at least 48 hours.)

Trial details

NCT IDNCT04019093

SponsorUniversity of Florida

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-04-30

Results submitted2023-02-27

View on ClinicalTrials.gov More Temporomandibular Joint Disorders trials