Motor Plasticity, Intermittent Hypoxia and Sleep Apnea (NCT04017767) | Clinical Trial Compass
CompletedNot Applicable
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea
United States30 participantsStarted 2021-07-16
Plain-language summary
The purpose of this study is to learn about the effect of sleep apnea and low oxygen on muscle strength and lung function in people with chronic spinal cord injury.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
. Self-reported history of unstable angina or myocardial infarction within the previous month,
. OSA that is being treated with positive airway pressure therapy,
. Women who know or suspect they may be pregnant or who may become pregnant,
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared hand grip strength and muscle electrical activity between spinal cord injury patients who have moderate to severe sleep apnea and those who don't — could you help me understand what those findings might mean for my own situation, given whether or not I have sleep apnea?
2Since this trial has already been completed, would it be worth asking if the results are published yet, and whether those findings could influence the rehabilitation approach my care team recommends for me?
3The trial focused on motor plasticity — the idea that the nervous system might be able to relearn or strengthen movement — so could you explain whether my level or type of spinal cord injury would make me a candidate for therapies based on that concept?
4This study used intermittent hypoxia, which involves briefly reducing oxygen levels to potentially stimulate motor recovery — is that something my care team considers safe to explore given my current breathing and cardiovascular health?
5Since the trial looked specifically at people with moderate to severe obstructive sleep apnea alongside spinal cord injury, should I be screened for sleep apnea, and could untreated sleep apnea be affecting my motor recovery right now?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The difference in Motor Function assessed via hand grip strength measured by maximum grip strength (MGS) between participants with moderate to severe OSA and without OSA.
Timeframe: Baseline
2
The difference in Motor Function assessed via hand grip strength measured by electromyographic (EMG) recordings between participants with moderate to severe OSA and without OSA.