UnknownNot Applicable

Probiotics Attenuate Postoperative Cognition Decline

China220 participantsStarted 2019-12-15

Plain-language summary

The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.

Who can participate

Age range65 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. . Age is greater than or equal to 65 years old
✓. . Can communicate normally
✓. . Selective knee ankle, hip replacement or lumbar open reduction and internal fixation under general anesthesia
✓. . ASA graded at I-II level
✓. . Patient or family informed consent

Exclusion criteria

✕. . Have a brain disease, or have a history of brain disease
✕. .MMSE check of less than 24 points.
✕. . History of neurological and psychological disorders including AD, stroke, psychosis
✕. . Serious hearing or visual impairment
✕. . Preoperative systolic blood pressure \>190mmhg, or diastolic blood pressure \>100mmhg
✕. . The patient or family refuses

What they're measuring

Incidence of POCD 7days after surgery

Timeframe: The seventh day after surgery

Trial details

NCT IDNCT04017403

SponsorRenJi Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-31

Contact for this trial

tang ying, Bachelor

13918859887 421941497@qq.com

View on ClinicalTrials.gov More Necrosis of Femoral Head trials