CompletedNot Applicable

An Evaluation of Folic Acid to Improve Endothelial Sensitivity to Shear Stress in Seniors

Canada44 participantsStarted 2019-09-09

Plain-language summary

The purpose of this study is to evaluate if folic acid improves endothelial sensitivity to shear stress in post-menopausal women.

Who can participate

Age range50 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ≥ 1-year amenorrhea * Body mass index ≤ 30 kg/m2 * Resting blood pressure \< 140 / \< 90 mmHg * Non-smoker (≥ 1-year) Exclusion Criteria: * Diagnosis of cardiac, vascular, respiratory, neurological or metabolic disease and/or a prescription of medications for the treatment of such diseases. * For female participants, hormonal replacement therapy within 1 year of enrolment in the study. * For female participants, having undergone an ovariectomy.

What they're measuring

Endothelial sensitivity to shear rate

Timeframe: Measured 2 hours after placebo or folic acid consumption

Trial details

NCT IDNCT04016090

SponsorMontreal Heart Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-03

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