CompletedNot Applicable

CI-AKI in Patients With Stable CAD and Comorbidities. Are we Doing Better?

1,023 participantsStarted 2012-05-16

Plain-language summary

Patients aged 18-89 with stable CAD and comorbidities receiving optimal medical treatment requiring PCI with iodinated contrast media. The aim of the study is to assess the prevalence of contrast-induced AKI in 2012-2013 and 2017 cohorts and to evaluate the potential risk factors of CI-AKI to better guide the prevention in patients of higher risk.

Who can participate

Age range

18 Years – 89 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Informed consent * Male and female patients 18 y. o. and older * Verified stable coronary artery disease (CAD) * Receiving optimal medical treatment and requiring percutaneous coronary intervention (PCI) with iodinated contrast media Exclusion Criteria: * Pregnancy, lactation * Conditions affecting the prognosis (kidney failure, liver failure, oncology) * Acute coronary syndrome (ACS) * Stroke * Contraindications to PCI * Therapy with nephrotoxic drugs during the enrolment which cannot be stopped * Refusal to sign the informed consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Overall mortality

Timeframe: 5 years

Cardiovascular mortality

Timeframe: 5 years

Myocardial infarction

Timeframe: 5 years

Stroke

Timeframe: 5 years

GI bleeding

Timeframe: 5 years

CABG

Timeframe: 5 years

PCI

Timeframe: 5 years

Trial details

NCT IDNCT04014153

SponsorI.M. Sechenov First Moscow State Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-10-19

View on ClinicalTrials.gov More Stable Angina trials

Plain-language summary

Who can participate

Age range

18 Years – 89 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.