CompletedNot Applicable

Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade

South Korea68 participantsStarted 2019-04-26

Plain-language summary

It is well known that magnesium enhances the effect of neuromuscular blocking agents such as rocuronium. However, it is not known how much magnesium can reduce neuromuscular blocking agents in maintaining deep neuromuscular blockade. Through this study, the investigators will quantitatively analyze the rocuronium saving effect of magnesium.

Who can participate

Age range20 Years – 80 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who undergo elective robot assisted radical prostatectomy, between 20 and 80 years with a American Society of Anesthesiologists physical status classification of I or II Exclusion Criteria: * Conduction abnormalities in preoperative EKG such as Atrioventricular block, sinus pause * Glomerular filtration rate \<60ml/min/1.73m2 * Allergy to rocuronium, sugammadex, magnesium * Medications that interfered with muscle activity * Neuromuscular disease * Hypermagnesemia

What they're measuring

rocuronium amount

Timeframe: perioperative - until 48hours

Trial details

NCT IDNCT04013243

SponsorSeoul National University Bundang Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-07-30

View on ClinicalTrials.gov More Magnesium Sulfate Causing Adverse Effects in Therapeutic Use trials