CompletedNot Applicable

The Effect of Premedication With Curcumin on Post-endodontic Pain

Egypt44 participantsStarted 2019-08-01

Plain-language summary

Will premedication with Curcumin in single endodontic treatment in patients having acute pulpitis in mandibular molars affect post- operative pain? This the present study hopes to bring an evidence based decision on the possibility of using curcumin as a premedication to reduce post-operative pain in single visit treatment of cases with acute pulpitis

Who can participate

Age range

22 Years – 55 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female * Patients with age range 20- 55y * Mandibular molars with acute pulpitis. * Teeth with mature root Exclusion Criteria: * Pregnant or lactating females * Teeth with non vital pulp * Non- restorable teeth * Medically compromised patients(diabetics-bleeding disorder- hypertensive ) * Patients with facial swelling or acute infection. * Previously endodontically treated teeth * Periodontally affected teeth. * Teeth with calcified root canals, root caries, internal or external root resorption, sign of crack formation and anatomic abnormalities. * Patients taking analgesic medication before 12hours.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

change in post operative pain after single endodontic visit

Timeframe: immediately and after 8,12,24,48 hours after completion endodontic treatment

Trial details

NCT IDNCT04012424

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-08-01

View on ClinicalTrials.gov More Acute Pulpitis trials