WithdrawnNot Applicable

Comparison of OpeN VErsus RoboTic Partial Nephrectomy

Stopped: The Ontario government is now funding robotic partial nephrectomies.

Canada0Started 2019-11-01

Plain-language summary

A prospective randomized controlled feasibility trial for patients undergoing partial nephrectomy for T1 renal masses at Princess Margaret. Participants will be randomized receive either open or robotic partial nephrectomy.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Radiologically characterized T1 renal mass * Elected for partial nephrectomy surgery * Under the care of a uro-oncologist at Princess Margaret Cancer Centre * Willing to comply with follow-up protocol * Capable of providing informed consent Exclusion Criteria: * Radiologically characterized tumours ≥ T1 * Unfit for general anesthetic * Unsuitable for robotic surgery (determined by treating physician) * Unwilling to comply with standardized follow-up protocol * Evidence of metastatic disease * Solitary kidney * Previous surgery on affected kidney * Multiple tumours * Known genetic syndromes predisposing to multiple renal tumours (e.g., VHL, TS, BHD) * Pregnancy * Inability to read, understand, and complete the questionnaires written in English

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Recruitment Potential

Timeframe: Study duration (2 years)

Suitability of secondary outcome measures

Timeframe: Study duration (2 years)

Resource Utilization - Operating Room/Robotic Studio Time Availability

Timeframe: Study duration (2 years)

Resource Utilization - Cost of Study Participation

Timeframe: Study duration (2 years)

Trial details

NCT IDNCT04011891

SponsorUniversity Health Network, Toronto

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-24

View on ClinicalTrials.gov More Renal Masses trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Recruitment Potential

Timeframe: Study duration (2 years)

Suitability of secondary outcome measures

Timeframe: Study duration (2 years)

Resource Utilization - Operating Room/Robotic Studio Time Availability

Timeframe: Study duration (2 years)

Resource Utilization - Cost of Study Participation

Timeframe: Study duration (2 years)