Wool Clothing for the Management of Childhood Atopic Dermatitis (DESSINE2)

Inclusion Criteria: * Is aged between 3 months and 5 years of age at the time of recruitment * Has moderate to severe eczema as determined by an EASI score of 7 or above at their initial visit * Has a legally acceptable representative capable of understanding the informed consent document and providing consent on the participants behalf Exclusion Criteria: * Has a known allergic contact dermatitis to wool or merino wool * Is unable to attend all scheduled visits * Has unstable eczema defined by an escalation of treatment requirements during the preceding 6 weeks. This would include flares of AD for any reason including infection, food allergy etc. * Use of systemic corticosteroids within 6 weeks of study start. * Any medical reason that is considered by the principal investigator to preclude enrolment.