CompletedNot Applicable

Tracheal Colonization and Outcome After Major Abdominal Cancer Surgery

120 participantsStarted 2008-01

Plain-language summary

The goals of this study were to investigate whether two anesthesia regimens, with and without N2O, and bacterial colonization influence respiratory complications after major abdominal surgery for cancer.

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients diagnosis of gastric cancer, or colorectal cancer or pancreatic cancer * Scheduled for major abdominal surgery with organ resections * Written informed consent * Nasopharyngeal smears taken in the preoperative area * Tracheal aspirates taken at the end of the surgical procedure Exclusion Criteria: * Patients unable to understand study protocol and patients who refused study participation at any time * patients with clinically or radiologically confirmed acute respiratory infections at admission * antibiotic therapy due to the respiratory infections a week prior to the surgery

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Number of the patients with postoperative pneumonia

Timeframe: Postoperative day 4

Number of the patients with productive cough and difficult expectoration

Timeframe: Postoperative day 4

Number of the patients with hoarseness

Timeframe: Postoperative day 4

Trial details

NCT IDNCT04002128

SponsorOsijek University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-03

View on ClinicalTrials.gov More Colorectal Neoplasms Malignant trials

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.