CompletedNot Applicable

Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy

Denmark73 participantsStarted 2019-05-23

Plain-language summary

Pathophysiology of perioperative fluid management in patients undergoing emergency laparotomy.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Adults (18 years or over) undergoing emergency high-risk abdominal surgery for following abdominal pathology:
✓. Perforated small intestine
✓. Perforated large intestine
✓. Perforated ulcer
✓. Intestinal obstruction
✓. Anastomotic leakage following elective surgery
✓. Provided verbal and written informed consent
✓. Must speak and understand the Danish language

Exclusion criteria

✕. Appendectomies, cholecystectomies, negative diagnostic laparoscopies/laparotomies, herniotomies without bowel resections, sub-acute internal hernias after gastric bypass surgery, sub-acute surgery for inflammatory bowel diseases.
✕. Primary surgery for intestinal ischemia, abdominal bleed
✕. Emergency re-operations after elective surgery owing to intraabdominal bleeding, paralytic/obstructive ileus, intestinal ischemia
✕. Reoperation owing to fascial separation with no other abdominal pathology identified and sub-acute colorectal cancer-surgery were excluded from the cohort. Sub-acute surgery was defined as surgery planned within 48 hours.
✕. Traumas, gynecological, urogenital and other vascular pathology, pregnant patients.
✕. Dementia and/or cognitive dysfunction (diagnosed).

What they're measuring

The fluid distribution, during the early perioperative period (≤ 5 days), in patients with intestinal perforation versus intestinal obstruction versus postoperative complications with peritonitis.

Timeframe: perioperative period

Trial details

NCT IDNCT03997721

SponsorCopenhagen University Hospital, Hvidovre

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-03-02

View on ClinicalTrials.gov More Intestinal Obstruction trials