Smartphone App for Taking Images of Conjunctivae (NCT03997487) | Clinical Trial Compass
TerminatedNot Applicable
Smartphone App for Taking Images of Conjunctivae
Stopped: Lack of funding
Tanzania125 participantsStarted 2019-07-08
Plain-language summary
Trachomatous inflammation-follicular (TF) is diagnosed by looking for clinical signs of infection of everted eyelids (conjunctivae) of children.
The overall objective of this project is to develop a smartphone application and assess its acceptability and feasibility.
Fieldwork will take place during routine Tropical Data trainings and population-based prevalence surveys supported by Tropical Data.
Healthy adult volunteers in London will have photos of their conjunctivae taken to develop the app initially, with iterative improvements to the app based on image quality achieved. For fieldwork, images of the conjunctivae of children will be have photos of their conjunctivae taken with a digital single lens reflex (DSLR) camera and the newly developed smartphone app. Grading of the photos will be compared with field grading, to compare grading agreement, to assess utility for supervision, quality assurance and training purposes.
Who can participate
Age range
1 Year
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Objectives 2.1 and 2.2:
* For the London-based app development, any eligible healthy adult who provides written informed consent will be eligible.
* For the field-based app development, any child aged 1-9 years being examined as part of the Tropical Data IGA test, or sampled as part of trachoma prevalence surveys, and for whom written informed consent has been provided by a guardian, will be eligible.
Objective 2.3:
* All Tropical Data trainers and trainees attending the Tropical Data (initial and refresher) training events and who provide written informed consent, will be eligible.
* Community leaders and children's guardians who provide written informed consent will be eligible.
Exclusion Criteria:
* For each of the objectives, if the inclusion criteria are not fulfilled, the participant will not be eligible to participate.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
TOols For Trachoma Elimination Endgame (TOFTEE) app image quality
Timeframe: 30 minutes
2
Kappa score of TOFTEE image compared with field grading
Timeframe: 5 minutes
3
Kappa score of TOFTEE image compared with DSLR grading
Timeframe: 5 minutes
4
Kappa score of DSLR image compared with field grading
Timeframe: 5 minutes
Trial details
NCT IDNCT03997487
SponsorLondon School of Hygiene and Tropical Medicine