Researching the Effect of Aerobic Exercise on Cancer (NCT03996239) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Researching the Effect of Aerobic Exercise on Cancer
United States38 participantsStarted 2019-06-20
Plain-language summary
This study is being done to answer the following question: Will aerobic exercise (exercise that stimulates and strengthens the heart and lungs, and improves the body's use of oxygen) change the biomarkers (signs of disease) found in the blood?
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Exclusion criteria
. Acute myocardial infarction within 3-5 days of any planned study procedures;
. Unstable angina
. Uncontrolled arrhythmia causing symptoms or hemodynamic compromise
. Recurrent syncope
. Active endocarditis
. Acute myocarditis or pericarditis
. Symptomatic severe aortic stenosis
. Uncontrolled heart failure
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is looking at variant allele frequency and residual tumor burden — can you explain what those measurements mean for my specific cancer, and why tracking them through aerobic exercise might matter for my situation?
2Since this trial is 'active but not recruiting,' it's already closed to new participants — are there similar studies on exercise and cancer biology that I might still be eligible to join?
3The trial doesn't appear to be testing a drug but rather aerobic exercise as an intervention — what level or type of physical activity would typically be involved in a study like this, and is that something that would even be safe for me right now given my current treatment?
4Given that this is a Phase NA trial focused on measuring biological markers rather than proving a treatment benefit, what would the findings from a study like this actually mean for how my cancer might be managed down the road?
5Would you recommend I prioritize standard treatment options right now, or is there value in finding an exercise-focused research study like this one as a complement to whatever treatment plan we're considering?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
number of patients with variant allele frequency (VAF)
Timeframe: 2 years
2
changes in residual tumor burden (Solid tumor group)