Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men (NCT03993483) | Clinical Trial Compass
CompletedNot Applicable
Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men
Canada20 participantsStarted 2018-06-01
Plain-language summary
Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively heavy loads. Whether or not performing resistance exercise with relatively heavy loads or light loads is equally as effective between the upper- and lower-body within the same individual has never been investigated. Given the substantial individual variance in resistance exercise training-induced changes in muscle mass and strength, this study is designed to quantify the relative influence that extrinsic training variables (e.g., load), as opposed to intrinsic muscle-based predisposition, has on resistance training-induced changes in muscle mass and muscle strength.
Who can participate
Age range
18 Years – 30 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Be between the ages of 18-30 years (inclusive)
* Be able to maintain a habitual diet and perform resistance exercise three times per week throughout the trial
* Be in general good health (assessed by Get Active Questionnaire)
* Understand the study procedures and sign this form providing informed consent to participate in the study.
Exclusion Criteria:
* Use of tobacco or related products
* A history of neuromuscular problems or muscle and/or bone wasting diseases
* Any acute or chronic illness; cardiac, pulmonary, liver, or kidney abnormalities; insulin- or non-insulin-dependent diabetes or other metabolic disorders (all ascertained through medical questionnaires)
* Use of medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatory drugs (prescription use or daily use of over the counter medication), or prescription strength acne medications)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.