CompletedNot Applicable

Effect of Vitamin D on the Size of Fibroids in Women With Vitamin D Deficiency

Spain15 participantsStarted 2019-07-09

Plain-language summary

Vitamin D supplementation in patients with uterine fibroids who present hypovitaminosis D to re-establish their normal serum values could stabilize the size of the uterine fibroids and thus prevent their growth or reduce their size thanks to the anti-proliferative action of Vitamin D on the myoma cells.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with at least one fibroid \> 3 cm * With hypovitaminosis D (25(OH)D \< 30 ng/ml) * BMI \< 30 * No hormonal treatment in the 3 months prior to the ultrasound study Exclusion Criteria: * Black race * Symptomatic fibroids subsidiary to hormonal or surgical treatment * Desire of gestation in the next 6 months * Presence of degenerating adenomyosis or fibroids * Treatment with sexual hormones: mifepristone, aGnRH or any other medication that may interfere with fibroids. * History of neoplasia of gynecological origin and/or existence of uterine malformations. * Hypercalcemia or abnormal liver or kidney function is present

What they're measuring

volume of the uterine fibroids

Timeframe: 3 months

Trial details

NCT IDNCT03991078

SponsorFundación IVI

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-25

View on ClinicalTrials.gov More Size of the Uterine Fibroids trials