StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord

Inclusion Criteria: * Pediatric patients between the ages of 2 years old and 17 years old * Patients diagnosed with primary CNS tumors including medulloblastoma, pineoblastoma, ependymoma, intracranial germ cell, glioma or intracranial sarcoma who will be starting proton CSI * Patients planned to receive at least 20 Gy CSI at 1.8 - 2.0 Gy per fraction * Patients with an identified adult (aged 18 years or older caregiver)(familial or other) who consents to apply the StrataXRT and placebo twice a day for the duration of the study and complete the study instruments * Informed consent by parents or legal guardian; consent documents will be translated with non-English speaking participants Exclusion Criteria: * Patients who have already started proton CSI treatment * Patients receiving \> 10 fractions photon therapy * Patients with pre-existing dermal scarring, as determined by a clinical member of the study staff * Patients who only have a primary caregiver who is a minor (e.g. mother under the age of 18) * Patients planned to receive less than 20 Gy CSI at 1.8-2.0 Gy per fraction