Treatment of Diabetic Foot Ulcers With Inforatio Technique to Promote Wound Healing

INCLUSION CRITERIA: We include diabetic patients with foot ulcers that are more than six weeks old and which are located distal to the malleoli. The diameters of the ulcers must be at least four mms. One wound from each foot of a patient can be included. If a patient's foot have more than one ulcer that meets the abovementioned criteria, the biggest wound is included. If there is no difference in size, the wound that has the most recent onset is included. If two wounds are close to each other and separated by less than 5 mm intact skin, we will consider it as one wound. Wound onset estimates will be patient-reported. EXCLUSION CRITERIA: We exclude following patients: * Patients with dementia and other patients who are not able to give their informed consent. * Patients with gangrene, necrosis deeper than 1mm, osteomyelitis and clinical signs of infection in their foot. Infection is identified by clinical assessment based on the classical signs comprising oedema, pain, warmth, redness and purulent exudates and is assessed by an experienced orthopedic surgeon. * Patients with ulcers that have positive probe-to-bone test and visible joint and tendons * Patients with systolic toe pressure of \< 20 mmHg * Patients that, since the onset of their present foot ulcer, underwent vascular surgery in the lower extremity with the same laterality as the foot ulcer. * Patients that, since the onset of their present foot ulcer, underwent surgical off-loading and amputations * Patients …