A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kid… (NCT03984409) | Clinical Trial Compass
CompletedNot Applicable
A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones
United States22 participantsStarted 2019-06-01
Plain-language summary
Patients with nephrolithiasis and evidence of hypocitraturia or aciduria who would otherwise be started on potassium citrate, can achieve similar urine alkalization with 500-1000 mL of daily low calorie orange juice consumption.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* • Between 18 and 75 year of age.
* History of kidney stone disease with available stone analysis
* Evidence of aciduria or hypocitraturia on 24 hour urinalysis (24 hr citrate male \<450 mg/day female \<550 mg/day) or aciduria (urine pH \< 5.8)
* Ability to drink Kroger low calorie orange juice beverage
* If subject with history of diabetes mellitus, must have HgA1c \< 7.5 and willing to check daily blood sugars.
Exclusion Criteria:
* • Less than 18 or older than 75 years of age
* Allergies to low calorie orange juice, including intolerance because of side effects including (but not limited to): gastrointestinal symptoms, headaches, weight gain, unable to drink because of taste.
* Poorly controlled diabetic (HgA1c \>7.5)
* No evidence of hypocitraturia or aciduria on 24 hour urinalysis
* Unable to afford potassium citrate therapy or tolerate medication because of side effects.
* Unwilling to perform 3 24-hour urine collections
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Urine alkalization from Kroger low calorie orange juice beverage
Timeframe: 9 weeks from enrollment
2
Urine alkalization from Kroger low calorie orange juice beverage