UnknownPhase 4

Botulinum Toxins Intralesional Injection for Scar Pain

Taiwan20 participantsStarted 2018-07-30

Plain-language summary

Botulinum toxins has been approved by the FDA to treat chronic migraine. Botox had been shown to inhibiting the release of inflammatory mediators and peripheral neurotransmitters from sensory nerve to treat neuropathic pain. In the clinical practice, botox indeed effect in scar pain. However, investigators need well controlled study to prove this finding and assess the improvement of scar appearance.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients have visible hypertrophic scars or keloids over three months after trauma or surgery.
. Patients have symptoms of pain, itching or erythema.

Exclusion criteria

. Patients had either Botulinum toxin type A or Triamcinolone intralesional before in the same scar
. The scar size is larger than 10 cm2
. Immunocompromised status
. Systemic infection status
. Allergic to Botulinum toxin type A or steroids

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Scar pain relief

Timeframe: Change from baseline scar pain during 16 weeks after drug injection

scar appearance

Timeframe: Change from baseline scar appearance during 16 weeks after drug injection

itch

Timeframe: Change from baseline itch sensation during 16 weeks after drug injection

Trial details

NCT IDNCT03982862

SponsorKaohsiung Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-06-30

Contact for this trial

Shu hung Huang, MD, PHD

886-3121101 huangsh63@gmail.com

View on ClinicalTrials.gov More Scar Keloid trials