Botulinum toxins has been approved by the FDA to treat chronic migraine. Botox had been shown to inhibiting the release of inflammatory mediators and peripheral neurotransmitters from sensory nerve to treat neuropathic pain. In the clinical practice, botox indeed effect in scar pain. However, investigators need well controlled study to prove this finding and assess the improvement of scar appearance.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Scar pain relief
Timeframe: Change from baseline scar pain during 16 weeks after drug injection
scar appearance
Timeframe: Change from baseline scar appearance during 16 weeks after drug injection
itch
Timeframe: Change from baseline itch sensation during 16 weeks after drug injection