Traumatic Brain Injury is a major health concern in United States. There is a un-met need to develop new therapeutic options for faster neuron recovery without causing significant side effects. The role of ketones in neuronal recovery has been studied and has been found to be useful in decreasing size of contusion. The present study aims to study the safety and feasibility profile of ketogenic diet.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this was an early Phase 1 trial studying the ketogenic diet in traumatic brain injury patients, what does the available safety data actually show — were there any concerning side effects from putting a TBI patient on a ketogenic diet while in acute care?
2The trial measured whether patients could actually develop ketosis in the blood and excrete ketones in the urine — do you know if the participants successfully reached ketosis, and does that tell us anything about whether this diet approach is even feasible for someone in my situation?
3One of the main things this study tracked was intracranial pressure — based on what was found, is there any signal that the ketogenic diet helped, had no effect, or possibly worsened pressure in the brain, and how should that influence my care decisions?
4Since this trial has already completed, have the results been published anywhere, and would it be worth reviewing them together to understand whether a ketogenic diet is something worth pursuing as part of my recovery plan?
5Given that this was a very early-phase study and standard TBI treatments are already established, do you think the evidence from this trial is mature enough to consider a ketogenic diet now, or would sticking with conventional nutritional support be the safer path for me?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Effect of Ketogenic Diet on Intracranial Pressure
Timeframe: Baseline, till patient on KD (maximim 1 month)
2
Development of Ketosis in blood
Timeframe: Baseline, till patient on KD ( maximum 1month)
3
Excretion of Ketones in Urine
Timeframe: Baseline, till patient on KD (maximum 1 month)