CompletedNot Applicable

Cardinality Matching Study of Early v.s. Delayed VV ECMO in Severe Respiratory Failure

667 participantsStarted 2011-12-01

Plain-language summary

Clinical reasoning and recent data suggest that early use of venovenous extracorporeal membrane oxygenation in refractory respiratory failure may confer a survival advantage. This retrospective matched study will assess whether patients who received VV ECMO at less severe hypoxaemia had differing outcomes to those who received ECMO with very severe hypoxaemia.

Who can participate

Age range16 Years

SexALL

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Inclusion Criteria: * Patients included in the UK ECMO registry (see previous registration; NCT number awaited; protocol ECMO-001) * Patients with VV ECMO Exclusion Criteria: * Patients with inadequate or missing data for creation of propensity score models.

What they're measuring

Survival to ECMO ICU discharge

Timeframe: Up to 90 days.

Trial details

NCT IDNCT03981393

SponsorUniversity of Cambridge

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-12-31

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