Active — Not RecruitingNot Applicable

Dietary Intake, Sarcopenic Obesity, and Other Treatment-Related Outcomes in Indian Children With Acute Lymphoblastic Leukemia

India115 participantsStarted 2019-04-18

Plain-language summary

Sarcopenic obesity occurs when there is a loss of muscle and gain of fat in the body. With this study, the investigators will explore how nutritional status at the beginning of the treatment can cause changes in your child's body fat compared to muscle in the body. The investigators will also look at how these changes can impact a child's cancer treatment, survival from treatment, and if there is any deterioration in health and nutrition status. The primary objective of this study is to establish the incidence of sarcopenic obesity, measured by dual-energy x-ray absorptiometry (DEXA), among Indian children and adolescents with acute lymphoblastic leukemia (ALL).

Who can participate

Age range5 Years – 15 Years

SexALL

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Inclusion Criteria: * Newly diagnosed with ALL * Able to consume ≥ 80% of dietary requirements enterally * Adequate performance status (Lansky score ≥70) * Receiving standard treatment for ALL on or as per the Indian Childhood Collaborative Leukemia Group's protocol (ICiCLe). Exclusion Criteria: * Refusal of consent * Relapsed ALL * Down's syndrome; (Other congenital anomalies too) * Therapy initiated elsewhere

What they're measuring

Incidence of Sarcopenic Obesity

Timeframe: 6 months

Trial details

NCT IDNCT03974893

SponsorColumbia University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10

View on ClinicalTrials.gov More Sarcopenic Obesity trials