The purpose of this retrospective and prospective project is to understand the molecular and genetic basis of liver cancer of childhood. Understanding the molecular and genetic bases of liver cancers can offer a better classification based on tumor biology, mechanisms and predisposition.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Gene sequencing
Timeframe: Recurrence free survival at 2 years
Gene expression analysis
Timeframe: Recurrence free survival at 2 years
Status of genome-wide chromatin accessibility
Timeframe: Duration of active chemotherapy to two years after surgical treatment
Epigenetic change
Timeframe: Duration of active chemotherapy to two years after surgical treatment
Tumor infiltrating cells which express immune checkpoints
Timeframe: Duration of active chemotherapy to two years after surgical treatment