CompletedNot Applicable

Castror Oil for Labor Induction in Women With Previous Cesarean Section

Egypt70 participantsStarted 2019-07-15

Plain-language summary

Nowadays, more and more women embark on pregnancy with previous Caesarean scar. One in five pregnancies requires induction of labour. The use of non-pharmacological methods (methods without using medication) has been gaining popularity for women who are not good candidates, such as women with previous Caesarean scar, for induction with medications such as prostaglandin. Labour induction with prostaglandin carries a higher risk of uterine rupture and thus it is not routinely offered to women with previous Caesarean delivery in Cairo University Hospital. Non-pharmacological methods of induction of labour appear to be safe in women with previous Caesarean delivery. However, various methods are available and the efficacy among them remain in doubt.

Who can participate

Age range20 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant women with one previous lower segment Caesarean section who are admitted to Cairo University Hospital for induction of labor (IOL) will be recruited. The inclusion criteria are age at least 20 years old, gestational age at recruitment from 36 weeks to 38 weeks ±6 days, gestational age at induction= 39 weeks, singleton pregnancy, reassuring fetal status, and Bishop score ≤ 6. Exclusion Criteria: * Prior high-risk uterine scar; uterine rupture, classical CS, hysterotomy, or myomectomy * Short inter-delivery interval (\<12 months) * Complications in the previous CS (e.g. puerperal sepsis) Obstetric indication for CS (either elective or emergency): * Placenta praevia * Placental abruption * Documented evidence of cephalopelvic disproportion * Fetal macrosomia (estimated fetal weight \>4 kg) * Fetal anomalies interfering with vaginal delivery e.g. hydrocephalus * Fetal distress or non-reassuring Cardiotocography pattern

What they're measuring

Percentage of women entering active phase within 24 hours of administering castor oil/placebo

Timeframe: two weeks

number of successful VBAC cases

Timeframe: 24 hours

Trial details

NCT IDNCT03958981

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-05-30