This study aims to specifically examine the in vivo electrophysiology and effects of direct stimulation of the human amygdala during conditioned and evoked fear. Investigators will also examine amygdala electrophysiology and the effects of stimulation during tasks to examine the effects of reward on fear memory. This study will recruit subjects with a history of temporal lobe epilepsy (TLE) who have undergone neurosurgical implantation with FDA-approved, NeuroPace RNS devices for treatment of seizures. These patients provide a unique cohort with (Responsive Neurostimulation) RNS devices capable of both recording and stimulating the amygdala during performance of fear-based, behavioral tasks.
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EEG(electroencephalography) amplitude changes
Timeframe: 2 days
EEG(electroencephalography) frequency changes
Timeframe: 2 days
ECoG (ElectroCorticoGraphy) amplitude changes
Timeframe: 2 days
ECoG (ElectroCorticoGraphy) frequency changes
Timeframe: 2 days