Obesity leads to a vicious circle that increases intramuscular fat, insulin resistance, promotes muscular dysfunction resulting in increased muscle fat accumulation. The study of muscle function and intramyocellular lipids is insufficient for obesity. Particularly, the study of mechanisms in muscle function and intramyocellular lipids is few nationally and internationally.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Total droplet area
Timeframe: Before intervention / after 12weeks intervention
Number of lipid droplets
Timeframe: Before intervention / after 12weeks intervention
Single muscle fiber cross-sectional area (CSA)
Timeframe: Before intervention / after 12weeks intervention
Single muscle fiber maximal force (Po)
Timeframe: Before intervention / after 12weeks intervention
Single muscle fiber specific force (SF)
Timeframe: Before intervention / after 12weeks intervention
Single muscle fiber maximal shortening velocity (Vo)
Timeframe: Before intervention / after 12weeks intervention
Single muscle fiber MHC type distribution
Timeframe: Before intervention / after 12weeks intervention