UnknownNot Applicable

Cutibacterium Acnes in Bone and Joint Infections

France50 participantsStarted 2019-06-15

Plain-language summary

Prosthetic Joint Infections (PJIs) are increasing with the use of orthopedic devices on an ageing population. Cutibacterium acnes is a commensal organism that plays an important role in the ecosystem healthy human skin, yet this species is also recognized as a pathogen in foreign body infection: endocarditis, prostatitis and specifically in PJIs. C. acnes is able to escape the immune system. This phenomenon could reflect two bacterial behavior: the bacterial internalization by host cells and the biofilm formation.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * bone infection with C. acnes, * isolation of the strain, * presence of a single species, * conservation of a viable strain, * patients over 18 years

What they're measuring

Internalization capacity of C. acnes strains

Timeframe: Day 0

Biofilm capacity of C. acnes strains

Timeframe: Day 0

Trial details

NCT IDNCT03950063

SponsorCHU de Reims

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-06-15

Contact for this trial

Xavier OHL

03 26 78 32 72 xohl@chu-reims.fr

View on ClinicalTrials.gov More Prosthesis and Bone Infections trials