CompletedPhase 4

Luteal Support in Frozen-Thawed Embryo Transfer Cycles

Turkey (Türkiye)151 participantsStarted 2021-06-30

Plain-language summary

This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles. Starting from day 11, group 1 will receive 100 mg micronized progesterone parenteral daily injections, group 2 will receive 90 mg bioadhesive gel vaginal twice daily and group 3 will receive 40 mg oral dydrogesterone daily tablets.

Who can participate

Age range20 Years – 40 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * woman aged 20-40 years * Having available blastocyst(s) cryopreserved by vitrification method. Exclusion Criteria: * requirement for fresh embryo(s); * presence of any clinically relevant systemic disease contraindicated for assisted reproduction or pregnancy * history of more than three failed cycles of IVF * history of recurrent abortions * allergy history for relevant drugs * body mass index of \<18 or \>38 kg/m2 at screening * current breastfeeding or pregnancy * refusal or inability to comply with the requirements of the protocol for any reason, including scheduled clinic visits and laboratory tests * trophectoderm or blastomere biopsy of the blastocyst(s) to be transferred

What they're measuring

ongoing pregnancy rate

Timeframe: 12th week of pregnancy

Trial details

NCT IDNCT03948022

SponsorCentrum Clinic IVF Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-18

View on ClinicalTrials.gov More Implantation; Placenta trials