CompletedNot Applicable

Impact of Parathyroidectomy on Cardiovascular Calcification in Dialysis-dependent Patients

Russia63 participantsStarted 2019-05-14

Plain-language summary

This is a prospective cohort study aimed to evaluate change of cardiovascular calcification after parathyroidectomy in patients with end-stage renal disease on dialysis compared with control group on conservative treatment.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age \> 18 years
✓. ESRD patients receiving long-term hemodialysis or peritoneal dialysis treatment
✓. Severe secondary hyperparathyroidism defined as iPTH level \> 800 pg/ml, followed with hypercalcemia and/or hyperphosphatemia; with presence of one or more nodular or diffuse parathyroid hyperplasia confirmed with CT

What they're measuring

Change in coronary artery calcium score measured with CT

Timeframe: 18 months

Change in vascular calcification score measured with semi-quantitative (Kauppila) test

Timeframe: 18 months

Trial details

NCT IDNCT03937349

SponsorSaint Petersburg State University, Russia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-01-18

View on ClinicalTrials.gov More Secondary Hyperparathyroidism trials