The Implementation of Real-time PCR - Intrapartum GBS (Group B Streptococcus) Colonization to Reduce Antibiotic Prophylaxis

inclusion criteria: * Pregnant patients that were screened positive by a culture at 35-37 weeks (those patients will be screened with a vaginal double swab upon admission to labor ward). * Pregnant patients with GBS bacteriuria in current pregnancy (those patients will be screened with a vaginal double swab upon admission to labor ward). * Pregnant patients in preterm labor before 37 weeks (those patients will be screened with a vaginal double swab upon admission to labor ward). * Pregnant patients with prolonged rupture of membranes (those patients will be screened with a vaginal double swab after 17 hours and prior to antibiotics treatment). * All patients have signed an informed consent. Exclusion Criteria: * Pregnant patients that do not want to participate in the study. * Pregnant patients that fever is the risk factor for GBS prophylaxis. * Pregnant patients that were screened negative by a culture at 35-37 weeks. * Pregnant patient with PPROM (before 34 weeks).