Circulating miRNA in Primary Hyperparathyroidism

Inclusion Criteria: * post menopausal * has had DXA scan * has 24 hr Urine Calcium * Elevated serum calcium * Vitamin D above 20 ng/ml * capable of giving informed consent * female * indication for biochemical primary hyperparathyroidism or an indication for partial or total thyroidectomy Exclusion Criteria: * history of ESRD on dialysis or renal osteodystrophy * prior parathyroidectomy * hyper or hypothyroid by TSH * currently taking steroids or has been on steroids for more than 7 days in the last two years * estrogen therapy within the last two years * bisphosphonate therapy within the last two years * diagnosis of Cushing's disease or Cushing's syndrome * taking biotin within 24 hours of blood draw