CompletedPhase 2/3

Vasopressin Injection Versus Misoprostol During Hysteroscopic Myomectomy In Reducing Blood Loss And Operation Time.

40 participantsStarted 2016-05-02

Plain-language summary

A prospective randomized study designed to compare the efficacy of transcervical vasopressin injection versus vaginal misoprostol in reducing intra -operative blood loss during hysteroscopic mymectomy .

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * symptomatic women presented with bleeding or infertility and scheduled for hysterscopic myomectomy * grade 0 and grade 1 submucous myomas * less than 5 centimeters in diameter Exclusion Criteria: * Patients with grade 2 submucous myoma or more * patients with submucous myomas larger than 5 cm in diameter * postmenopausal women * patients received GnRh analogue in last 6 months * patients with anticoagulant therapy * patients with endometrial premalignant or malignant pathologies * patients with cardiovascular diseases, asthma or impaired kidney functions

What they're measuring

intraoperative bleeding

Timeframe: start with the first resectoscope myoma cut till withdrawal of hysterscope through the cervix at the end of the procedure

operative time

Timeframe: start with insertion of hysterscope through the cervix ends with withdrawal of hysterscopy through the cervix at the end of the procedure

haemoglobin and hematocrit deficit

Timeframe: 24 hours before myomectomy and 24 hour after myomectomy

Trial details

NCT IDNCT03930069

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2017-01-30

View on ClinicalTrials.gov More Submucous Leiomyoma of Uterus trials