Community-associated Highly-Resistant Enterobacterales

Inclusion Criteria: Category 1: Patients who live at home and meet the following criteria: * CDC-defined HRE isolated during a previous hospitalization or outpatient visit * Home origin * First positive HRE culture within 48 hours of admission (in case of hospitalization) Category 2: Hospitalized patients with CDC-defined HRE isolated during hospitalization who are not discharged home and who meet any of the following criteria: * Admitted from other care facility (not home origin) * Do not have first positive HRE culture within 48 hours of admission Category 3: Patients with CDC-defined HRE isolated during a previous hospitalization or outpatient visit who are eventually discharged home and who meet any of the following criteria: * Admitted from other care facility (not home origin) * Do not have first positive HRE culture within 48 hours of admission (in case of hospitalization) Category 4: Participants who meet the following criteria: • Community contact of a participant in Category 1 and/or 3. Exclusion Criteria: In all categories, participants who meet the following criteria will be excluded: • Age \<18 years In category 1, the following are exclusionary: * pre-existing renal failure * pre-existing liver disease * immunocompromised * history of malignancy * pregnancy In addition, in category 1, 3 and 4, who meet the following criteria will be excluded: • Unable to provide informed consent