Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery

Inclusion Criteria: * At least 18 years or older * Diagnosed with severe kidney dysfunction (defined by plasma creatinine clearance \<30 mL/min) * Planning on kidney transplantation surgery at the University of Colorado Hospital. Exclusion Criteria: * Patients unable to sign the informed consent * Pregnant women * Body Mass Index (BMI) \> 40 kg/m2 * Pre-existing oxygen or ventilatory dependency (24h use of oxygen or other noninvasive or invasive ventilatory support) * Patients with any pulmonary, neuromuscular or other disease that severely limits their respiratory functional status (e.g. unable to achieve 4 Metabolic Equivalent of Tasks, METs, such as climbing up 1 flight of stairs) * Presence of any contraindication for any of the study-related medications or interventions.