UnknownNot Applicable

Clinical Effect of APRF With DFDBA Compare to Collagen Membrane With DFDBA in Intraosseous Defect

Egypt22 participantsStarted 2019-09-30

Plain-language summary

to assess the effectiveness of advanced PRF in combination of Demineralized freeze-dried bone allograft (DFDBA) as compared to collagen membrane in combination with Demineralized freeze-dried bone allograft (DFDBA) treatment of non-contained periodontal intraosseous defects in stage III periodontitis patients.

Who can participate

Age range25 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Stage III periodontitis patient having at least one tooth with one wall or combined1- to 2-wall intraosseous defect ≥ 3 mm deep (assessed by trans-gingival probing, radiographic examination) with clinical attachment level (CAL) ≥ 5mm and pocket depth (PD) ≥ 6 mm. * Defect not extending to a root furcation area * Vital teeth * Non-smokers. * No history of intake of antibiotics or other medications affecting the periodontium in the previous 6 months. * No periodontal therapy carried out in the past 6 months. * Able to sign an informed consent form. * Patients age between 25 and 50 years old. * Patients who are cooperative, motivated, and hygiene conscious. * Systemically free according to Cornell Medical Index Exclusion Criteria: * Pregnancy or breast feeding * The presence of an orthodontic appliance * Teeth mobility greater than grade I

What they're measuring

Change in clinical attachment level (CAL)

Timeframe: CAL will be measured at base line, 3, 6, 9, 12 months postoperative

Trial details

NCT IDNCT03922503

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-30

View on ClinicalTrials.gov More Intrabony Periodontal Defect trials